MAIN KEGG FILE RESULTS

	WEB-based GEne SeT AnaLysis Toolkit

	*Translating gene lists into biological insights...*

User data and parameters: User data: textAreaUpload.txt, Organism: hsapiens, Id Type: ensembl_gene_stable_id, Ref Set: entrezgene, Significance Level: Top10, Statistics Test: Hypergeometric, MTC: BH, Minimum: 2

This table lists the enriched KEGG pathways, number of Entrez IDs in your user data set for the pathway, the corresponding Entrez IDs, and the statistics for the enriched pathway.
The statistic column lists:

C: the number of reference genes in the category
O: the number of genes in the gene set and also in the category
E: the expected number in the category
R: ratio of enrichment
rawP: p value from hypergeometric test
adjP: p value adjusted by the multiple test adjustment

Finally, the pathway name is linked to KEGG where the user ids are highlighted, the number of user gene ids is linked to a table with information about the user ids, and the Entrez IDs are linked to Entrez Gene.

PathwayName	#Gene	EntrezGene	Statistics
Hedgehog signaling pathway	3	655 7474 51715	C=56;O=3;E=0.19;R=15.61;rawP=0.0010;adjP=0.0170
Alanine, aspartate and glutamate metabolism	2	84706 2875	C=32;O=2;E=0.11;R=18.21;rawP=0.0054;adjP=0.0306
Endocytosis	4	9727 3306 79720 30011	C=201;O=4;E=0.69;R=5.80;rawP=0.0052;adjP=0.0306
Sphingolipid metabolism	2	130367 9331	C=40;O=2;E=0.14;R=14.57;rawP=0.0084;adjP=0.0357
Metabolic pathways	8	84706 3141 2875 230 10654 9791 23475 9331	C=1130;O=8;E=3.88;R=2.06;rawP=0.0417;adjP=0.0788
Regulation of actin cytoskeleton	3	56924 10552 2257	C=213;O=3;E=0.73;R=4.10;rawP=0.0373;adjP=0.0788
TGF-beta signaling pathway	2	4052 655	C=84;O=2;E=0.29;R=6.94;rawP=0.0339;adjP=0.0788
Fc gamma R-mediated phagocytosis	2	255189 10552	C=94;O=2;E=0.32;R=6.20;rawP=0.0416;adjP=0.0788
Peroxisome	2	55825 10654	C=79;O=2;E=0.27;R=7.38;rawP=0.0303;adjP=0.0788
Toxoplasmosis	2	596 3306	C=132;O=2;E=0.45;R=4.42;rawP=0.0758;adjP=0.1030

WebGestalt is currently developed and maintained by Jing Wang and Bing Zhang at the Zhang Lab. Other people who have made significant contribution to the project include Dexter Duncan, Stefan Kirov, Zhiao Shi, and Jay Snoddy.

Funding credits: NIH/NIAAA (U01 AA016662, U01 AA013512); NIH/NIDA (P01 DA015027); NIH/NIMH (P50 MH078028, P50 MH096972); NIH/NCI (U24 CA159988); NIH/NIGMS (R01 GM088822).